Cryocompression To Reduce Neuropathy Caused by Chemotherapy
We're doing this study to find out if using ice with or without compression during chemotherapy can prevent neuropathy for patients being treated for gynecologic cancer.
About This Study
Summary
This study, conducted in partnership with Duke University, is evaluating whether cryotherapy alone or cryotherapy combined with compression (cryocompression) can reduce the development and severity of peripheral neuropathy in patients with gynecologic cancers receiving taxane-based chemotherapy.
If you choose to participate, you'll be randomly assigned (like a coin flip) to either receive cryotherapy alone or cryotherapy with compression during chemotherapy infusions. All participants will wear their ice packs on their hands and feet (with or without compression) for the duration of each of their infusions. We will ask a few questions at the start of the infusion about your neuropathy symptoms and a few questions about your experience after the infusion is done.
To be included in Cryocompression, participants must be / have:
- Diagnosed with a gynecological cancer
- Receiving a taxane chemotherapy for the first time
- Scheduled to have at least 6 cycles of a taxane chemotherapy
To be included in Cryocompression, participants must not be / have:
- Received prior chemotherapy
- Existing diagnosis of peripheral neuropathy such as diabetic neuropathy, or conditions including but not limited to fibromyalgia, cryoglobulinemia, and Raynaud’s disease
Keywords
Chemotherapy; Cryotherapy; Neuropathy
For More About This Study or To Ask About Participation
Additional Information
Lead scientist at Carilion Clinic
Dr. Erin Saks is the section chief of gynecologic oncology, as well as the medical director of the outpatient infusion center and cancer genetics program. She's board certified by the American Board of Obstetrics and Gynecology in obstetrics and gynecology and gynecologic oncology. She completed her fellowship at University of Virginia and completed her internship and residency with Brown University’s Alpert School of Medicine at Women and Infants hospital of Rhode Island. Dr. Saks joined the faculty of the department of obstetrics and gynecology in 2018 and is an assistant professor at the Virginia Tech Carilion School of Medicine.
Official title of study
Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer
Industry sponsored by Duke Cancer Institute
National Clinical Trials listing
IRB approval number and responsible organization
IRB-25-1957 Carilion Clinic