
IRB Members
General guidance and educational resources for IRB members.
What is an IRB?
IRB Members
Each Carilion Clinic Institutional Review Board (IRB) has at least five members, with varying backgrounds to provide adequate review of research activities commonly conducted at Carilion. Members include scientists, non-scientists and individuals who are not affiliated with the institution. The unaffiliated member represents the perspective of research subjects when reviewing submissions before the IRB.
If you have questions about Carilion Clinic IRB membership, please send us an email at irb@carilionclinic.org.
Chair of the Carilion Clinic IRB
Charles J. Schleupner, MSc, MD, FACP, FIDSA, FSHEA
IRB Chair
540-981-7490
cjschleupner@carilionclinic.org
Contact Dr. Schleupner for information regarding human research subjects' protections or rights.
Dr. Schleupner is professor of Internal Medicine at the Virginia Tech Carilion School of Medicine. He is on the medical staff at Carilion Roanoke Memorial Hospital and the Salem Veterans Affairs Medical Center. He has received numerous grants for research studies in virology and infectious diseases. He received his medical degree from the University of Maryland and completed his internal medicine residency and a fellowship in infectious diseases at the University of Utah Medical Center. He received a master’s degree in microbiology from the University of Pittsburgh Graduate School of Public Health.
General Guidance for Board Members
How do I use the PRIS3M IRB application system?
All submissions come through the PRIS3M online submission system. The PRIS3M system is used by IRB members for review of research applications.
To access the PRIS3M system, sign in with your Carilion Clinic Active Directory username and password.
If you are a new IRB member and do not have an Active Directory username and password, we will work with you to have one created and will let you know when you are able to log in to the system.
Click the PRIS3M Application System button below for access to the online submission system.
Are there specific education and training requirements for IRB members, program staff and leadership?
The link below describes the education requirements for members of the Carilion Clinic IRB, Human Research Protections Office staff and leadership.
Education and Training Expectations
What duties will I be expected to perform when reviewing research proposals?
An outline of the duties required of IRB members, alternates, consultants and institutional representatives can be accessed at the link below.
What should I do if I think I have a conflict of interest?
The link below defines circumstances under which Carilion IRB members will be considered to have a conflict of interest and describes how the situation will be handled.
Educational Resources for Board Members
IRB members are provided with ongoing educational opportunities that highlight regulatory information, scientific discoveries and trending topics in research. The educational videos and presentations linked below highlight information provided at monthly IRB meetings.
2025 Meetings
November: National Advisory Committee on Human Research Protections (NACHRP) October: Repository & Open-Ended Consent September: Federal Science Policy Changes "Restoring Gold Standard Science" Executive Order June: Federal Policy Impacts May: Quick Reference for IRB Members--Evaluating Medical Devices in Human Subjects Research April: Declaration of Helsinki Revisions 2024 March: Understanding Research Non-Compliance February: Pervasive Data January: Assessing & Evaluating Key Elements of Informed Consent Process
2024 Meetings
2023 Meetings
October: Research Ethics September: IRB Review Process for Continuing Reviews July: Adverse Event Reporting July: Capacity, Vulnerability, and Informed Consent for Research June: Consent Appropriately Sought and Documented May: Adequate measures to protect privacy and confidentiality April: Data Safety Monitoring March: Subject Selection is Equitable and Free of Coercion February: Risks are reasonable in relation to benefits January: Expanded role of IRBs for Biopsies