
DLIF on Functional Performance
The primary objective of this study is to determine if the timeline of functional performance recovery differs between direct lateral interbody infusion (DLIF)/posterior spinal fusion (PSF) and PSF alone.
About This Study
Summary
The primary objective of this study is to determine if the timeline of functional performance recovery differs between direct lateral interbody infusion (DLIF)/posterior spinal fusion (PSF) and PSF alone. The secondary objectives will be to determine if DLIF is associated with acute post-operative deficits in lower extremity function, and to determine the association between patient reported outcomes and lower extremity function scores. The results of this study will help inform patients, clinicians, and physical therapists of potential performance limitation after DLIF.
Participants will complete functional movement tasks that align with standard of care post-operative appointment schedules. Functional movement tasks will include self-selected walking speed, a series of balance tests, performance on a stair climbing task, and hip flexion and knee extension strength. Patient reported outcome tools (questionnaires) will also be obtained at each timepoint, including a visual analog pain scale, a general health/wellness survey and a survey specific to lower extremity function.
To be included in DLIF on Functional Performance, participants must be / have
- 45-80 years old
- Surgical intervention for DLIF or PSF
- Able to adhere to pre- and post-operative visit schedule
To be included in DLIF on Functional Performance, participants must not be / have
- Underlying lower extremity conditions that would hinder ability to complete functional performance tasks
- Preexisting physical or cognitive limitations
- Documented history of illicit drug or alcohol abuse
For More About This Study or To Ask About Participation
Additional Information
Lead scientist at Carilion Clinic

Jonathan Carmouche, MD, is a spine surgery and scoliosis specialist. Dr. Carmouche is the section chief of orthopaedic spine at Carilion Clinic and a professor of orthopaedic surgery at Virginia Tech Carilion School of Medicine.