Carilion Clinic Cardiology research spans the spectrum from large, multicenter randomized clinical trials to smaller studies conceived and conducted by Carilion cardiologists.
Our studies are sponsored by the National Institutes of Health, by device and pharmaceutical companies, by agencies such the American Heart Association and by foundations. Our overall goal is to participate in and conduct studies that will answer important questions in cardiovascular medicine.
Clinical Trials
- PARADIGM Evaluating AVP III following surgical valve replacement
- ENCIRCLE Evaluating mitral valve replacement through the femoral artery
- Cerclage EFS Study
- Randomized Clinical Evaluation of the AccuCinch® Ventricular Restoration System (5019) in Patients who Present with Symptomatic HFrEF
- Early Feasibility Study of the AccuCinch® Ventricular Restoration System in Patients with Heart Failure and Reduced Ejection Fraction (5017) (HFrEF)
- Early Feasibility Study of the AccuCinch® Ventricular Restoration System (5018) in Patients with Prior Mitral Valve Intervention (PMVI) and Recurrent Mitral Regurgitation
- Evaluation Aortic Replacement Surveillance Asymptomatic (EARLY TAVR)
- NHLBI DIR LAMPOON Study
- COAPT Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients
- ASAP-TOO Assessment of the WATCHMAN™ Device in Patients Unsuitable for Oral Anticoagulation
Coronary artery disease is the narrowing or blockage of the coronary (heart) arteries. This condition is usually caused by atherosclerosis. Atherosclerosis is the buildup of cholesterol and fatty deposits (called plaques) inside the arteries.
Heart failure, sometimes known as congestive heart failure, occurs when your heart muscle doesn't pump blood as well as it should. Certain conditions, such as narrowed arteries in your heart (coronary artery disease) or high blood pressure, gradually leave your heart too weak or stiff to fill and pump efficiently.
A humanitarian use device (HUD) is a medical device intended to benefit patients in the treatment or diagnosis of a disease or condition. Because usage numbers are too small to study in a large clinical trial, they are approved by the FDA for use on a limited basis.
